Publications

2026年

S-acylation and membrane localization of the small GTPase ARL15 are mediated by the Golgi S-acyltransferases ZDHHC7 and ZDHHC3

Chino T, Araki M, Ashi Y, Izawa Y, Nunami Y, Ichikawa Y, Kuroiwa I, Kontani K.
J Biol Chem. 2026:111460. doi: 10.1016/j.jbc.2026.111460

PMID: 41999893

Functional sQTLs regulating PTK2B exon 31 splicing uncover an RNA-dependent modulation of its kinase activity and cellular phenotype

Kato M, Isazawa A, Ohki A, Fujita A, Araki M, Yanaizu M, Kino Y.
Cell Commun Signal. 2026; . doi: 10.1186/s12964-026-02835-x

PMID: 41928225

2025年

Quantifying small GTPase activation status using a novel fluorescence HPLC-based assay

Araki M, Kasuya Y, Yoshimoto K, Katada T, Kontani K.
J Biol Chem. 2025:108545. doi: 10.1016/j.jbc.2025.108545.

PMID: 40286847

Calmodulin enhances mTORC1 signaling by preventing TSC2-Rheb binding

Amemiya Y, Ioi Y, Araki M, Kontani K, Maki M, Shibata H, Takahara T.
J Biol Chem. 2025;301(2):108122. doi: 10.1016/j.jbc.2024.108122.

PMID: 39716490

The a subunit isoforms of V-ATPase are involved in glucose-dependent trafficking of insulin granules

Sekiya M, Nakanishi-Matsui M, Matsumoto N, Takahashi I, Hanasaka T, Ishiyama-Matsuura E, Araki M, Wakayama T, Nata K
Sci Rep. 2025;15(1):18982. doi: 10.1038/s41598-025-02997-7.

PMID: 40447629

2024年

Analysis of the Guanine Nucleotide-Bound State of KRAS by Ion-Pair Reversed-Phase High-Performance Liquid Chromatography

Araki M, Kontani K.
Methods Mol Biol. 2024;2797:227-236. doi: 10.1007/978-1-0716-3822-4_16.

PMID: 38570463

2023年

Translational regulation and protein-coding capacity of the 5' untranslated region of human TREM2

Yanaizu M, Adachi H, Araki M, Kontani K, Kino Y.
Commun Biol. 2023;6(1):616. doi: 10.1038/s42003-023-04998-6.

PMID: 37291187

2021年

Development of a versatile HPLC-based method to evaluate the activation status of small GTPases

Araki M, Yoshimoto K, Ohta M, Katada T, Kontani K
J Biol Chem. 2021;297(6):101428. doi: 10.1016/j.jbc.2021.101428.

PMID: 34801548

Caenorhabditis elegans PTR/PTCHD PTR-18 promotes the clearance of extracellular hedgehog-related protein via endocytosis

Chiyoda H, Kume M, Cadena del Castillo C, Kontani K, Spang A, Katada T, Fukuyama M
PLoS Genet. 2021;17(4):e1009457. doi: 10.1371/journal.pgen.1009457.

PMID: 33872306